1239279-30-1

SSR-241586 is an antagonist of neurokinin receptors. SSR-241586 is shown to be active in the treatment of depression, schizophrenia, urinary trouble, emesis, and irritable bowel syndrome (IBS)[1][2].

[1] Métro TX, et al. Asymmetric synthesis of an antagonist of neurokinin receptors: SSR 241586. J Org Chem. 2011 Apr 15;76(8):2594-602. DOI:10.1021/jo102471r
[2] Cochi A, et al. Enantioselective synthesis of SSR 241586 by using an organo-catalyzed Henry reaction. Org Lett. 2010 Aug 20;12(16):3693-5. DOI:10.1021/ol101555g