Lexitropsin 1 is a DNA minor groove binder with a delta G degree of 65 kJ/mol at 303 K. Lexitropsin 1 has antiviral activity[1].
target
Lexitropsin 1 is a novel anticancer agent.
References
[1] S Kumar, et al. Structural and dynamic aspects of non-intercalative (1:1) binding of a thiazole-lexitropsin to the decadeoxyribonucleotide d-[CGCAATTGCG]2: An 1H-NMR and molecular modeling study. J Biomol Struct Dyn. 1991 Aug;9(1):1-21. DOI:10.1080/07391102.1991.10507890
