122876-48-6

Latrunculins A is a novel marine toxin that disrupt microfilament organization in cultured cells.

6,7-Epoxy-latrunculin A can be isolated from the Red Sea sponge Negombata magnifica and is initially identified as an inhibitor of actin polymerization by its morphological effects[1].

[1] James D. White, et al. Total synthesis of (+)-latrunculin A, an ichthyotoxic metabolite of the sponge Latrunculia magnifica and its C-15 epimer. The Journal of Organic Chemistry. 1992.