Pacidamycin I is an antimicrobial nucleoside antibiotics that acts by inhibiting the clinically unexploited target translocase I, a key enzyme in peptidoglycan assembly. It is an essential pharmacophore isolated from Streptomyces coeruleorubidus.
Uses
Pacidamycin I (A-68567) is a nucleoside peptide antibiotic that is highly specific for Pseudomonas aeruginosa[1].
References
[1] Karwowski, et al. PACIDAMYCINS, A NOVEL SERIES OF ANTIBIOTICS WITH ANTl-PSEUDOMONAS AERUGINOSA ACTIVITY I. TAXONOMY OF THE PRODUCING ORGANISM AND FERMENTATION. The Journal of antibiotics 42.4 (1989): 506-511. DOI:10.7164/antibiotics.42.506
