1176470-37-3

Prostaglandin D₁(PGD₁) alcohol is the synthetic analog of PGD₁ with a primary alcohol in place of the C-1 carboxyl. There are no known reports of its biological activity. PGD₁ is the theoretical D-series metabolite of dihomo-γ-linolenic acid (DGLA), but to date it has not been isolated as a natural product. It is an inhibitor of ADP-induced platelet aggregation in humans with an IC₅₀ value of 320 ng/ml, about 1/10 as potent as PGD₂.¹

1. Bundy, G.L., Morton, D.R., Peterson, D.C., et al. Synthesis and platelet aggregation inhibiting activity of prostaglandin D analogues J. Med. Chem. 26(6),790-799(1983).