1169831-01-9

SL-017, also known as ACP-SL-017; ACPSL-017; ACP-SL-017, is a Hypocrellin-B (HB) derivative and photosensitiser potentially for the treatment of hair growth abnormality. SL017 treatment resulted in increased mitochondrial fragmentation which followed loss of ΔΨm. SL017 targets mitochondria, triggering collapse of mitochondrial membrane potential, generates ROS and subsequently results in mitochondrial fragmentation.