Uses
Synthetic nonsteroidal ecdysone agonist causing premature molting; novel insect growth regulator specific to lepidopteran species. Insecticide.
Uses
Tebufenozide is used to control lepidopterous larvae on rice, fruit,
row crops, nut crops, vegetables and vines and in forestry.
Definition
ChEBI: A carbohydrazide that is hydrazine in which the amino hydrogens have been replaced by tert-butyl, 3,5-dimethylbenzoyl and 4-ethylbenzoyl groups respectively. It is an insecticide used widely against caterpillars.
Hazard
Low toxicity by ingestion, inhalation, and
skin contact.
Agricultural Uses
Insecticide, Insect growth regulator: Tebufenozide is an insect growth regulator that interferes
with molting of Lepidopteran larvae. It is used on
fruitworm, fireworms, false armyworm, gypsy moth, and
spanworms, and is applied pre-harvest. Registered for use
in EU countries. Registered for use in the U.S.
Trade name
CONFIRM®; MIMIC®; RH-5992®
Metabolic pathway
Oxidation of ethyl and methyl substituents of the phenyl rings of
tebufenozide occurs in soils and plants, to give carboxylic acids, alcohols
and a ketone.
Degradation
Tebufenozide was stable at 94 °C for 7 days, stable to light in pH 7
aqueous solution (25 °C) and stable in dark sterile water for 30 days
(25 °C). The DT50 in natural pond water, in light, was 30 days (25 °C)
(PM). It was stable in acidic and neutral buffer solutions. Hydrolysis
was marked in alkaline conditions (DT50 203 days, pH 10, 20°C).
Tebufenozide was stable in sterilised stream water in the dark but
degraded in non-sterile water (DT50 181 days). The insecticide was
photodegraded by sunlight (DT50 83 hours, summer 46°N). The
results suggest that microbial degradation and photolysis will be the
main routes of tebufenozide dissipation in natural aquatic conditions
(Sundaram, 1994).
