111337-86-1

Sperabillin A (free base) is an antibacterial antibiotic with potent in vivo activity, isolated from Pseudomonas fluorescens YK-437.

Sperabillin A is an antibacterial agent against gram-positive and gram-negative bacteria. Sperabillin A shows strong inhibition of human umbilical vein endothelial (HUVE) cell proliferation. Sperabillin A also shows anti-tumor acfivity against B16 melanoma in mouse[1].

[1] Hida T, et al. Chemistry and anti-tumor activity of sperabillin polymers. Chem Pharm Bull (Tokyo). 1993 May;41(5):889-93. DOI:10.1248/cpb.41.889