LB-205 is a pan-histone deacetylase inhibitor (HDACi). LB-205 can be used for the research of acute traumatic brain injury[1][2].
References
[1] Lu J, et, al. Histone deacetylase inhibitors are neuroprotective and preserve NGF-mediated cell survival following traumatic brain injury. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52. DOI:10.1073/pnas.1308950110 [2] Lu J, et, al. Histone deacetylase inhibitors prevent the degradation and restore the activity of glucocerebrosidase in Gaucher disease. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5. DOI:10.1073/pnas.1119181109
