1110905-26-4

MTBT is an inhibitor of the proliferation of cancer cells. It induces cell cycle arrest and activates p38 MAPK.

MTBT is an anticancer agent and p38 activator with antiproliferative and apoptosis-inducing (apoptosis) activities. MTBT increases the phosphorylation of histone H3 serine in cancer cells, thereby arresting the cell cycle in the M phase. SB203580 (HY-10256), a specific inhibitor of p38 MAPK, abolished MTBT-induced cell cycle arrest[1].

[1] A small molecule, MTBT, prevents cancer cell growth by activating p38 MAPK