1087243-14-8

GRL-0496 (1087243-14-8) is a potent (IC50?= 30 nM in cell culture assays) inhibitor of severe acute respiratory syndrome-coronavirus chymotrypsin-like protease (SARS-CoV 3CLpro).1

ChEBI: (5-Chloropyridin-3-yl) 1H-indole-4-carboxylate is an indolyl carboxylic acid. It has a role as an anticoronaviral agent.

Store at -20°C

1)????Ghosh?et al. (2008),?Design, synthesis and antiviral efficacy of a series of potent chloropyridyl ester-derived SARS-CoV 3CLpro inhibitors;?Bioorg. Med. Chem.Lett,?18?5684