108-43-0

Name 3-Chlorophenol
CAS 108-43-0
EINECS(EC#) 203-582-6
Molecular Formula C6H5ClO
MDL Number MFCD00002256
Molecular Weight 128.56
MOL File 108-43-0.mol

Chemical Properties

Appearance All isomers have a characteristic odor.
Melting point  31-34 °C (lit.)
Boiling point  214 °C (lit.)
density  1.218 g/mL at 25 °C(lit.)
vapor pressure  1 hPa (44 °C)
refractive index  n20/D 1.563(lit.)
Fp  >230 °F
storage temp.  2-8°C
solubility  Soluble in ethanol and ether.
form  Liquid After Melting
pka 8.85(at 25℃)
color  Clear yellow to brownish
Odor distinct phenol-like odor
PH 3.5 (27.7g/l, H2O, 20℃)
Stability: Stable. Combustible. Incompatible with acid chlorides, oxidizing agents, acid anhydrides. Discolours in air.
Water Solubility  27.7 g/L (20 ºC)
Detection Methods GC
Merck  14,2154
BRN  1634401
InChI 1S/C6H5ClO/c7-5-2-1-3-6(8)4-5/h1-4,8H
InChIKey HORNXRXVQWOLPJ-UHFFFAOYSA-N
SMILES Oc1cccc(Cl)c1
CAS DataBase Reference 108-43-0(CAS DataBase Reference)
NIST Chemistry Reference Phenol, 3-chloro-(108-43-0)
EPA Substance Registry System 108-43-0(EPA Substance)

Safety Data

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)Environment (GHS09)
GHS05,GHS07,GHS09
Signal word  Danger
Hazard statements  H302+H312+H332-H315-H318-H411
Precautionary statements  P273-P280-P301+P312-P302+P352+P312-P304+P340+P312-P305+P351+P338
Hazard Codes  Xn,N
Risk Statements 
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .
Safety Statements 
S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
RIDADR  UN 2020 6.1/PG 3
WGK Germany  2
RTECS  SK2450000
F  9
Autoignition Temperature >600 °C
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29081000
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Aquatic Chronic 2
Eye Dam. 1
Skin Irrit. 2
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion and subcutaneous routes. Questionable carcinogen with experimental tumorigenic data by skin contact. Mutation data reported. Flammable or combustible liquid. When heated to decomposition it emits toxic fumes of Cl-. See also CHLOROPHENOLS.
Hazardous Substances Data 108-43-0(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 0.57 g/kg (Deichmann)

Hazard Information

Material Safety Data Sheet(MSDS)

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