Chemical Properties
Cyclopentadecanolide occurs in small quantities in,
for example, angelica root oil. It forms colorless crystals (mp 37–38°C) with a
delicate, musk-like odor.
Chemical Properties
white crystalline low melting solid
Chemical Properties
ω-Pentadecalactone has an extraordinarily persistent, musk-like odor.
Occurrence
Originally reported found in the essential oil from angelica roots.
Uses
As a fixative in perfumery.
Application
Cyclopentadecanolide gives highly interesting effects when applied to certain flavors,
e. g. alcoholic beverages, dentifrice flavors etc.
There is very often a unanimous preference
for the flavor that is properly treated with the
hctone. Concentration in such flavors may be about
0.02 to 1.50 ppm calculated upon the finished
consumer product. However, it should be
kept in mind, that dentifrices are flavored at
extremely high concentration (about 100) and
it may therefore ghe an underestimated evaluation of the power of this Lactone, The most
frequent abuse of Cyclopentadecanolide is
that of over-dosage. It is also used extensively in Berry flavors, Liquor, Wine, Brandy, Fruit, Nut, Vanilla copositions, etc.
Definition
ChEBI: Cyclopentadecanolide is a macrolide.
Preparation
The main industrial syntheses start from compounds produced
from cyclododecatriene: either by ring expansion of cyclododecanone or
by depolymerization of polyesters of 15-hydroxypentadecanoic acid (from
1,12-dodecanediol).
Aroma threshold values
Detection: 1 to 4 ppb
Taste threshold values
Taste characteristics at 75 ppm: vanilla bean, powdery helioropine, creamy and licorice.
General Description
Pentadecanolide is one of the major components, isolated from the root of Angelica archangelica L., species. It is a synthetic musk, which exists as a widespread contaminant in the environment.
Flammability and Explosibility
Nonflammable
Trade name
Macrolide® (Symrise), Exaltolide®, Exaltolide®Total (Firmenich),
Pentalide (Soda Aromatic).
Purification Methods
It has been recrystallised from MeOH (4 parts) at -15o. [Hundieck
