Definition
ChEBI: Flumioxazin is a benzoxazine that is N-(prop-2-yn-1-yl)-2H-1,4-benzoxazin-3(4H)-one which is substituted at position 6 by a 1,3-dioxo-1,3,4,5,6,7-hexahydro-2H-isoindol-2-yl group and at position 7 by a fluorine. A protoporphyrinogen oxidase inhibitor, it is used for the control of weeds in soya, peanuts, and a variety of vegetable and fruit crops. It has a role as a herbicide, an agrochemical, an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor and a teratogenic agent. It is a benzoxazine, a terminal acetylenic compound, a dicarboximide and an organofluorine compound.
Metabolic pathway
When the rats are given a single oral dose of 14C-S-
53482, seven metabolites are identified in the urine
and the feces. Alcohol derivatives and the acetoanilide
derivative are isolated from the urine, and three
sulfonic acid conjugates with a sulfonic acid group
incorporated into the double bond of the 3,4,5,6-
tetrahydrophthalimide moiety are isolated from the
feces.
