Potential Exposure
Calcium chloride is used as road salt
for melting snow, a drying agent in desiccators, for dehydrating organic liquids and gases, in refrigeration brines
and antifreeze, as a dust-proofing agent, food additives,
concrete hardening accelerator, and others. May react with
strong oxidizers.
First aid
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts
the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from
exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has
stopped and CPR if heart action has stopped. Transfer
promptly to a medical facility. When this chemical has
been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit
Shipping
There are no label or maximum shipping quantity requirements set by DOT.
Incompatibilities
The solution in water is a weak base.
Reacts with zinc in presence of moisture, forming highlyflammable hydrogen gas. Dissolves violently in water
with generation of much heat. Incompatible with water,
bromine trifluoride; 2-furan, percarboxylic acid. May
attack some building materials and metals in the presence
of moisture.
Chemical Properties
Calcium chloride is a colorless to off-white
crystalline solid which is deliquescent (absorb water).
When heated, crystals lose water @ 100C.
Definition
ChEBI: A hydrate that is the dihydrate form of calcium chloride.
Brand name
Cal Plus (Mallinckrodt).
Biological Functions
Calcium chloride is a commonly used reagent in biochemistry. Calcium plays important roles in many biological processes, including signal transduction, muscle contraction, and maintenance of cell membrane and cell wall stability.Extensive reviews of the experimental measurement of biological calcium have been published.
Calcium chloride is used in the preparation and transformation of competent E. coli and in the transfection of eukaryotic cells with either plasmid DNA or high molecular weight genomic DNA.The CaCl2-mediated electroporation of E. coli with the plasmid DNA pBR322 has been studied.A protocol for the concentration of virus vectors that uses CaCl2 has been published.
CaCl2 has been used in the stabilization and twodimensional crystallization of the NADH-ubiquinone oxidoreductase (complex I) from Escherichia coli. The crystallization of porcine pancreatic elastase in the presence of CaCl2 in the presence of sodium citrate reveals binding of calcium in the metal binding site of the protein.The effect of CaCl2 on the total fluorescence in the polymerication of the tubulin-like FtsZ division protein of Escherichia coli has been studied by a multiwell fluorescent assay.
Biochem/physiol Actions
Calcium chloride act as precipitants during protein crystallization process. It also enhances the competence of Escherichia coli cells as well as strengthened β-lactoglobulin gels by forming crossbridges.
Properties and Applications
|
ITEMS
|
SPECIFICATION
|
|
APPEARANCE
|
WHITE,HARD ODORLESS FLAKE,
POWDER,PELLET,GRANULE
|
|
CALCIUM CHLORIDE(As CaCl2)
|
77% min
|
|
MAGNESIUM&ALKALI METAL SALT (As NaCl)
|
4.0% max
|
|
WATER INSOLUBLE MATTER
|
0.2% max
|
|
ALKALINITY(As Ca(OH)2)
|
0.15% max
|
|
SULFATE (As CaSO4)
|
0.25% max
|
|
pH VALUE
|
7-11
|
|
As
|
5 ppm max
|
|
Pb
|
10 ppm max
|
|
Fe
|
10 ppm max
|
Purification Methods
Crystallise it from ethanol. It is hygroscopic. It loses H2O at 200o so it can be dried at high temperatures to dehydrate it. The hexahydrate [7774-34-7] has m 30o and d 1.67.
