100-40-3

Colorless liquid. Floats on water.

VINYLCYCLOHEXENE(100-40-3) can react with oxidizing materials. VINYLCYCLOHEXENE(100-40-3) is also incompatible with peroxide catalysts. Prolonged exposure to oxygen-containing gases leads to discoloration and gum formation. .

Highly flammable. This chemical oxidizes in air to form hydroperoxides. Slightly soluble in water.

Exposure can cause irritation of eyes, nose and throat. High concentrations have a narcotic effect.

4-Vinyl-1-cyclohexene is used as an intermediate for the production of vinylcyclohexene dioxide, which is used as a reactive diluent in epoxy resins. Previous uses of 4-vinyl-1-cyclohexene include comonomer in the polymerization of other monomers and for halogenation to polyhalogenated derivatives which are used as flame retardants.

Skin Contact: Flood all areas of body that have contacted the substance with water. Don’t wait to remove contaminated clothing; do it under the water stream. Use soap to help assure removal. Isolate contaminated clothing when removed to prevent contact by others. Eye Contact: Remove any contact lenses at once. Flush eyes well with copious quantities of water or normal saline for at least 20-30 minutes. Seek medical attention. Inhalation: Leave contaminated area immediately; breathe fresh air. Proper respiratory protection must be supplied to any rescuers. If coughing, difficult breathing or any other symptoms develop, seek medical attention at once, even if symptoms develop many hours after exposure. Ingestion: If convulsions are not present, give a glass or two of water or milk to dilute the substance. Assure that the person’s airway is unobstructed and contact a hospital or poison center immediately for advice on whether or not to induce vomiting.

UN1993 Flammable liquids, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid, Technical Name Required.

Vapor may form explosive mixture with air. Hydrolyzes in water. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, amines, alcohols.

4-Vinyl-1-cyclohexene, a cyclic alkene, is a highly flammable liquid.

Liquid. Temperatures above 80F (26.6C) and prolonged exposure to oxygen-containing gases should be avoided because these conditions lead to discoloration and gum formation.

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

ChEBI: 4-Vinylcyclohexene is a cyclic olefin.

4-Vinylcyclohexene is produced by dimerization of butadiene, as a by-product of chlorination of butadiene, or frombutadiene on long storage.

Journal of the American Chemical Society, 108, p. 1322, 1986 DOI: 10.1021/ja00266a047
Synthesis, p. 1027, 1984

A dose of 145 g/kg applied to mouse skin for 54 weeks provided weak evidence of carcinogenicity (109). Administration by gavage of doses of 0, 200, or 400 mg/kg body weight, 5 days per week, to groups of 50 F344/N rats for 103 weeks induced a slightly increased incidence of epithelial hyperplasia of the forestomach (1/50; 3/50; 5/47) and squamous cell papillomas or carcinomas (combined) of the skin, in males receiving the highest dose. Low-dose female rats whose survival was more similar to that of the vehicle controls had a marginally increased incidence of adenomas or squamous cell carcinomas (combined) of the clitoral gland. Under these conditions, the 2-year gavage studies in male and female rats were considered inadequate because of extensive and early mortality at the high dose or at body doses and the lack of conclusive evidence of a carcinogenic effect (125a). In female Fisher 344 rats treated with this agent to induce ovarian failure followed by application of the carcinogen dimethylbenzanthracene (DMBA) directly to the ovaries, there resulted tumors in 42% of animals at 3 months and 57% at 5 months (126b). All neoplasms were classified Sertoli–Leydig cell tumors (SLCT). No tumors occurred in animals treated with vehicle or DMBA alone.