VASP 兔单克隆抗体

背景资料

Vasodilator-stimulated phosphoprotein （VASP） belongs to the Ena/VASP family of adaptor proteins linking the cytoskeletal system to the signal transduction pathways. VASP functions in cytoskeletal organization， fibroblast migration， platelet activation and axon guidance. Three phosphorylation sites， Ser157， Ser239 and Thr278， have been identified. Evidence suggests that VASP phosphorylation reduces its association with actin and has a negative effect on actin polymerization.

应用类型

Western blotting （0.5-4 ug/ml）. However， the optimal conditions should be determined individually. Other applications have not been determined. The antibody recognizes ~46 kDa VASP from samples of human， mouse， and rat origins. Reactivity to other species has not been tested.

免疫原

Synthetic peptide surrounding amino acid 371 of human VASP

来源宿主

兔

反应性

经检测验证，可与人、小鼠、大鼠种属来源的VASP蛋白发生免疫反应.

保存建议

提供的VASP抗体产品为100 ug 无色溶液，其浓度为0.5 mg/ml，溶解于包含有30%甘油， 0.5% BSA和0.01%硫柳汞的PBS （pH 7.2）缓冲液中.请将该VASP抗体产品置于-20 ℃冷冻保存，建议分装使用以避免反复冻融.