aladdin 阿拉丁 I303791 ISO-1,细胞渗透性MIF拮抗剂 478336-92-4 99%

中文名：ISO-1,细胞渗透性MIF拮抗剂

英文名：ISO-1

中文别名：2-[3-(4-羟苯基)-4,5-二氢异恶唑-5-基]乙酸甲酯

英文别名：ISO-1|478336-92-4|MIF Antagonist, ISO-1|methyl 2-(3-(4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)acetate|MIF Antagonist|5-Isoxazoleacetic acid, 4,5-dihydro-3-(4-hydroxyphenyl)-, methyl ester|7QFF3Z0V9X|ISO 1|CHEMBL210858|MFCD22376813|4,5-DIHYDRO-3-(4-HYDROX

纯度：99%

货号：I303791

包装：25mg、5mg、100mg

Cas号：478336-92-4

存储温度：-20°C储存,充氩

产品介绍：

A cell-permeable isoxazoline compound that displays anti-inflammatory properties. Inhibits MIF dopachrome tautomerase activity by binding to its catalytic active site (IC50 = 7 µM for D-dopachrome tautomerase) and suppresses the production of TNFα, PGE2 and COX-2 in human monocytes and arachidonic acid in RAW 264.7 macrophages. Shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic mouse model.

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