Anti-Cyclin A1 antibody-周期素A1蛋白抗体 新品

Rabbit  Anti-Cyclin A1  Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:Cyclin A1

IR:Immunogen Range:391-465/465

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:8900

Swiss Prot:P78396

Source:KLH conjugated synthetic peptide derived from human Cyclin A1 :391-465/465 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Cyclin A1 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A1 is expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. It binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Cyclin A1 was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins.

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Cow
Rabbit
Sheep

仅供科研使用。不能用于人和动物治疗等其它临床诊断用！