Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
Home > 17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole > 17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole(17230-88-5)

17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole(17230-88-5)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
17beta-Hydroxy-2,4,17alpha-pregnadien-20-yno[2,3-d]isoxazole
Synonyms
17b-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole
Danazol
Danocrine
Danol
Pregna-2,4-dien-20-yno[2,3-d]isoxazol-17-ol, (17a)-
CAS
17230-88-5
Formula
C22H27NO2
Molecular Weight
337.46
EINECS
241-270-1
RTECS
TU4157070
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
Merck
12,2875
Beilstein/Gmelin
1088173
Beilstein Reference
5-27

Physical and Chemical Properties

Solubility in water
Insoluble
Melting Point
225
Boiling Point
478
Vapor Pressure
6E-10 (25 C)
pKa/pKb
13.10 (pKa)
Heat Of Vaporization
78.2 kJ/mol
Usage
Weak androgen and anterior pituitary suppressant.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Exposure Effects
Harmful. Possible risk of harm to the unborn child. Harmful by inhalation, in contact with skin and if swallowed. Calif. Prop. 65 reproductive hazard. Target organ(s): Female reproductive system. Pituitary.

Fire Fighting Measures

Flash Point
243
Fire Fighting
Extinguish using Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Hazards Identification

Hazards
Emits toxic fumes under fire conditions.
EC Risk Phrase
20/21/22 63
EC Safety Phrase
22 36
Contact More