Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > Dimethyl fumarate > Dimethyl fumarate(624-49-7)

Dimethyl fumarate(624-49-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Dimethyl fumarate
Synonyms
(2E)-2-Butenedioic acid dimethyl ester
Allomaleic acid dimethyl este
Boletic acid dimethyl ester
Dimethyl trans-ethylenedicarboxylate
Methyl fumarate
trans-Butenedioic acid dimethyl ester
CAS
624-49-7
Formula
C6H8O4
Molecular Weight
144.13
EINECS
210-849-0
RTECS
EM6125000
RTECS Class
Primary Irritant
Merck
13,4308
Beilstein/Gmelin
774590
Beilstein Reference
4-02-00-02205
EC Class
harmful, irritant, sensitizing

Physical and Chemical Properties

Appearance
White crystalline powder.
Solubility in water
Soluble
Melting Point
102
Boiling Point
192
Vapor Pressure
0.48 (25 C)
Density
1.37 g/cm3 (20 C)
Partition Coefficient
.62
Heat Of Vaporization
42.9 kJ/mol
Usage
Used to treat psoriasis.
Vapor Density
5
Refractive Index
1.4037 (110.7 C)

First Aid Measures

Ingestion
Never give anything by mouth to an unconscious person. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Get medical aid if irritation or symptoms occur.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Eyes
Get medical aid. Gently lift eyelids and flush continuously with water. Extensive irrigation is required (at least 30 minutes).

Handling and Storage

Storage
Store in a cool, dry place. Keep container closed when not in use. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
Inhalation
Inhalation of dust may cause respiratory tract irritation.
Skin
Causes skin irritation. May be harmful if absorbed through the skin. May cause reddening of the skin.
Eyes
Contact produces irritation, tearing, and burning pain. Causes severe eye irritation and possible injury.
EC Risk Phrase
R 21 36/37/38
EC Safety Phrase
S 26 36/37/39

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear safety glasses and chemical goggles if splashing is possible. Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Poison Class
4

Fire Fighting Measures

Flash Point
91
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Disposal Code
3
Incompatibilities
Acids - bases - oxidizing agents - reducing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code
2917 19 90
Contact More