Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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1-(4-Methoxybenzoyl)-2-pyrrolidinone(72432-10-1)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
1-(4-Methoxybenzoyl)-2-pyrrolidinone
Synonyms
1-(4-Methoxybenzoyl)-2-pyrrolidinone
1-(4-Methoxybenzoyl)pyrrolidin-2-one
1-p-Anisoyl-2-pyrrolidinone
Draganon
Ro-13-5057
Sarpul
CAS
72432-10-1
Formula
C12H13NO3
Molecular Weight
219.24
RTECS
UY5781900
Merck
12,700
Beilstein/Gmelin
4807205

Physical and Chemical Properties

Appearance
White solid.
Solubility in water
3.3 g/L
Melting Point
121 - 122
Boiling Point
400
Vapor Pressure
1.3E-6 (25 C)
Density
1.24 g/cm3 (20 C)
pKa/pKb
15.74 (pKb)
Partition Coefficient
.27
Heat Of Vaporization
65.05 kJ/mol
Usage
Has shown potential as an anxiolytic.

First Aid Measures

Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Handling and Storage

Storage
Keep container tightly closed.

Hazards Identification

Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
Skin
May cause skin irritation. May be harmful if absorbed through the skin.
Eyes
May cause eye irritation.
Hazards
Emits toxic fumes under fire conditions.

Exposure Controls/Personal Protection

Personal Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks.
Exposure Effects
Target organ: Central Nervous System.

Fire Fighting Measures

Flash Point
196
Fire Fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.

Accidental Release Measures

Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.

Stability and Reactivity

Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.
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