Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 3alpha,7alpha-Dihydroxy-5beta-cholanic acid > 3alpha,7alpha-Dihydroxy-5beta-cholanic acid(474-25-9)

3alpha,7alpha-Dihydroxy-5beta-cholanic acid(474-25-9)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
3alpha,7alpha-Dihydroxy-5beta-cholanic acid
Synonyms
17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7a-diol
3a,7a-Dihydroxy-5b-cholanoic acid
7a-Hydroxylithocholic acid
Anthropodesoxycholic acid
Chenodesoxycholic acid
Cholan-24-oic acid, 3,7-dihydroxy-, (3a,5b,7a)-
CAS
474-25-9
Formula
C24H40O4
Molecular Weight
392.57
EINECS
207-481-8
RTECS
FZ1980000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,2096
Beilstein/Gmelin
3219887
Beilstein Reference
4-10-00-01604

Physical and Chemical Properties

Appearance
White solid.
Solubility in water
Insoluble
Melting Point
164.85 - 165.85
Density
1.162 g/cm3
pKa/pKb
4.76 (pKa)
Usage
Bile acid. A detrrgent used to solubilize fats. Used as cholagogue, a choleretic laxative, and to prevent or dissolve gallstones.

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Use only in a chemical fume hood.

Hazards Identification

Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Chronic ingestion may cause liver damage. Prolonged or repeated exposure may cause adverse reproductive effects.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
No data.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, carbon dioxide.
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