Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione > 9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione(50-02-2)

9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione(50-02-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
9alpha-Fluoro-11beta,17alpha,21-trihydroxy-16alpha-methylpregn-1,4-diene-3,20-dione
Synonyms
Aphthasolone
Deltafluorene
Gammacorten
Prednisolone F
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11b,16a)-
Visumetazone
CAS
50-02-2
Formula
C22H29FO5
Molecular Weight
392.47
EINECS
200-003-9
RTECS
TU3980000
RTECS Class
Drug; Mutagen; Reproductive Effector; Human Data; Hormone
Merck
12,2986
Beilstein/Gmelin
2066651

Physical and Chemical Properties

Appearance
Odorless white to off-white crystalline powder with a slightly bitter taste.
Solubility in water
Insoluble
Melting Point
268 - 271
pKa/pKb
12.14 (pKa)
Usage
Medication.

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid immediately.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with skin and eyes. Avoid ingestion and inhalation. Use only in a chemical fume hood.

Hazards Identification

Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
Causes skin irritation.
Eyes
Causes eye irritation.
Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.

Exposure Controls/Personal Protection

Personal Protection
If Tyvek-type disposable protective clothing is not worn during handling of this chemical, wear disposable Tyvek-type sleeves taped to your gloves.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
seizures have been reported following pulse methylprednisolone therapy.

Fire Fighting Measures

Fire Fighting
Fires involving this material can be controlled with a dry chemical, carbon dioxide or Halon extinguisher. A water spray may also be used.
Fire Potential
This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Has not been fully evaluated.
Incompatibilities
Strong oxidizing agents.
Decomposition
Hydrogen chloride, carbon monoxide, oxides of nitrogen, carbon dioxide.
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