Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
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4-Pregnene-3,20-dione(57-83-0)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
4-Pregnene-3,20-dione
Synonyms
(8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
Pregn-4-ene-3,20-dione
CAS
57-83-0
Formula
C21H30O2
Molecular Weight
314.47000000000003
EINECS
200-350-6
RTECS
TW0175000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
Merck
12,7956
Beilstein/Gmelin
1915949

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Melting Point
127-131
Density
1.17 g/cm3 (25 C)
Usage
The major progestational steroid.
Refractive Index
1.5204

First Aid Measures

Ingestion
Get medical aid. Wash mouth out with water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Remove contaminated clothing and shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container. Hormones and antibiotics room.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Store protected from light. Use only in a chemical fume hood.

Hazards Identification

Inhalation
May cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
Harmful if swallowed. May cause irritation of the digestive tract.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear chemical goggles. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
A NIOSH/MSHA approved air purifying dust or mist respirator or European Standard EN 149.
Exposure Effects
Possible cancer hazard based on tests with laboratory animals.
Exposure limit(s)
OSHA: Possible Select carcinogen

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray, dry chemical, or carbon dioxide.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.

Stability and Reactivity

Stability
Stable in air; sensitive to light.
Incompatibilities
Strong oxidizing agents, light.
Decomposition
Carbon monoxide, carbon dioxide.
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