Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > Chloromycetin > Chloromycetin(56-75-7)

Chloromycetin(56-75-7)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
Chloromycetin
Synonyms
2,2-Dichloro-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide
Amphenicol
Amseclor
Chlomycol
D-Chloramphenicol
D-Threo-Chloramphenicol
CAS
56-75-7
Formula
C11H12Cl2N2O5
Molecular Weight
323.13
EINECS
200-287-4
RTECS
AB6825000
RTECS Class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Natural Product
Merck
13,2087
Beilstein/Gmelin
2225532
Beilstein Reference
4-13-00-02742

Physical and Chemical Properties

Appearance
Pale yellow plates or needles from water. White/gray/yellow powder.
Solubility in water
2.5 g/L (25 C)
Melting Point
150
Boiling Point
645
Vapor Pressure
2E-17 (25 C)
Density
1.49 g/cm3
pKa/pKb
11.03 (pKa)
Partition Coefficient
1.02
Heat Of Vaporization
100.0 kJ/mol
Usage
Medication.
Vapor Density
11.1
Refractive Index
1.5403 (164 C)

First Aid Measures

Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. If irritation develops, get medical aid.

Handling and Storage

Storage
Store in a cool, dry place. Store in a tightly closed container. Store protected from light.
Handling
Wash hands before eating. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use with adequate ventilation. Store protected from light.

Hazards Identification

Inhalation
May cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause liver damage. May cause hemorrhaging of the digestive tract. Exposure may cause anemia and other blood abnormalities.
EC Risk Phrase
R 40
EC Safety Phrase
S 22 36/37
UN (DOT)
1851

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
May cause cancer in humans.

Fire Fighting Measures

Flash Point
344
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities
Acids, acid chlorides, acid anhydrides and oxidizing agents.
Stability
Stable under normal shipping and handling conditions.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide.

Transport Information

UN Number
1851
Contact More