Home > 4-Nitrophenyl isocyanate > 4-Nitrophenyl isocyanate(100-28-7)
4-Nitrophenyl isocyanate(100-28-7)
Product Identification
Physical and Chemical Properties
First Aid Measures
Handling and Storage
Hazards Identification
Exposure Controls/Personal Protection
Fire Fighting Measures
Accidental Release Measures
Stability and Reactivity
Transport Information
Product Identification
Product Name
4-Nitrophenyl isocyanate
4-Nitrophenyl isocyanate
Synonyms
1-Isocyanato-4-nitrobenzene
p-Nitrophenylisocyanate
1-Isocyanato-4-nitrobenzene
p-Nitrophenylisocyanate
CAS
100-28-7
100-28-7
Formula
C7H4N2O3
C7H4N2O3
Molecular Weight
164.13
164.13
EINECS
202-836-3
202-836-3
RTECS
DA3692500
DA3692500
RTECS Class
Other
Other
Beilstein/Gmelin
389516
389516
Beilstein Reference
4-12-00-01653
4-12-00-01653
Physical and Chemical Properties
Appearance
Yellow, odorless solid.
Yellow, odorless solid.
Solubility in water
Insoluble
Insoluble
Melting Point
55 - 56
55 - 56
Boiling Point
277
277
Vapor Pressure
0.005 (25 C)
0.005 (25 C)
Partition Coefficient
2.96
2.96
Heat Of Vaporization
51.5 kJ/mol
51.5 kJ/mol
Vapor Density
5.7
5.7
First Aid Measures
Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.
Handling and Storage
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Hazards Identification
Inhalation
May cause respiratory tract irritation. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
May cause respiratory tract irritation. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
Skin
May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
May cause skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
Eyes
May cause eye irritation. Lachrymator.
May cause eye irritation. Lachrymator.
Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed.
Hazards
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
Vapors form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff.
EC Risk Phrase
R 20/22 36/37/38 42
R 20/22 36/37/38 42
EC Safety Phrase
S 22 26 36/37/39 45
S 22 26 36/37/39 45
UN (DOT)
2206
2206
Exposure Controls/Personal Protection
Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Exposure Effects
Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.
Repeated or prolonged exposure may cause allergic reactions in sensitive individuals.
Fire Fighting Measures
Flash Point
121
121
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Accidental Release Measures
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Clean up spills immediately, using the appropriate protective equipment. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability and Reactivity
Incompatibilities
Oxidizing agents.
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Stable under normal temperatures and pressures.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Combustion Products
Fire will produce irritating, corrosive and/or toxic gases.
Fire will produce irritating, corrosive and/or toxic gases.
Transport Information
UN Number
2206
2206
Hazard Class
6.1
6.1
Packing Group
II; III
II; III