Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide > 1,2-Benzisothiazol-3(2H)-one 1,1-dioxide(81-07-2)

1,2-Benzisothiazol-3(2H)-one 1,1-dioxide(81-07-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
1,2-Benzisothiazol-3(2H)-one 1,1-dioxide
Synonyms
1,2-Benzisothiazol-3(2H)-one 1,1-dioxide
1,2-Dihydro-2-ketobenzisosulfonazole
Anhydro-o-sulfaminebenzoic acid
o-Benzoic sulfimide
Saccharin acid
Saccharinose
CAS
81-07-2
Formula
C7H5NO3S
Molecular Weight
183.19
EINECS
201-321-0
RTECS
DE4200000
RTECS Class
Tumorigen; Mutagen; Reproductive Effector
Merck
12,8463
Beilstein/Gmelin
6888
Beilstein Reference
4-2700-02649

Physical and Chemical Properties

Appearance
White crystals. Odorless or faintly aromatic odor. Sweet taste.
Solubility in water
3.3 g/L
Melting Point
225 - 227
Boiling Point
sublimes
Density
0.828 g/cm3 (20 C)
pKa/pKb
1.31 (pKa)
Partition Coefficient
.91
Usage
Non-caloric synthetic sweetener.
Refractive Index
1.5878 (20 C)

First Aid Measures

Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Wash mouth out with water. Get medical aid if irritation or symptoms occur.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid breathing dust, vapor, mist, or gas. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.
Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. May be harmful if swallowed.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Exposure Effects
May cause cancer according to animal studies. May cause reproductive and fetal effects. Laboratory experiments have resulted in mutagenic effects.
Exposure limit(s)
OSHA: Possible Select carcinogen.

Fire Fighting Measures

Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire Potential
This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Transport Information

HS Code
2925 11 00
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