Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information
Home > 2-Desoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose > 2-Desoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose(18883-66-4)

2-Desoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose(18883-66-4)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Transport Information

Product Identification

Product Name
2-Desoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose
Synonyms
1-Methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
D-Glucose, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-
CAS
18883-66-4
Formula
C8H15N3O7
Molecular Weight
265.22000000000003
EINECS
242-646-8
RTECS
LZ5775000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data
Merck
12,8991
Beilstein/Gmelin
2060674

Physical and Chemical Properties

Appearance
Off-white powder.
Solubility in water
Soluble
Melting Point
184
pKa/pKb
9.36 (pKa)
Usage
Antibiotic.

First Aid Measures

Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage
Store at unopened vials in the refrigerator. Once reconstituted with 5% dextrose or saline in sterile water, the solution may be kept 24 hours under refrigeration.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Hazards Identification

Inhalation
Irritating substances may induce pulmonary edema or pneumonitis. Embolization of insolouble material may occur.
Skin
Avoid any skin contact. See Inhalation.
Eyes
See Inhalation.
UN (DOT)
3249

Exposure Controls/Personal Protection

Personal Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Exposure Effects
The toxological properties of this substance have not been fully investigated.
Exposure limit(s)
OSHA: Possible Select carcinogen.

Fire Fighting Measures

Fire Fighting
Use method most appropriate to fight surrounding fire.
Fire Potential
Non-Combustible

Accidental Release Measures

Small spills/leaks
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.

Stability and Reactivity

Stability
No data.
Incompatibilities
Reacts exothermically with acids Reacts with both strong oxidizing agents and strong reducing agents.
Combustion Products
Fire may produce irritating, corrosive and/or toxic gases.

Transport Information

UN Number
3249
Hazard Class
6.1
Packing Group
II; III
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