Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification
Home > 17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol > 17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol(57-63-6)

17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol(57-63-6)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity Hazards Identification

Product Identification

Product Name
17a-Ethynyl-1,3,5(10)-estratriene-3,17b-diol
Synonyms
17-Ethinyl-3,17-estradiol
17-Ethinylestradiol
19-Norpregna-1,3,5(10)-trien-20-yne-3,17-diol, (17a)-
Dyloform
Follicoral
Primogyn
CAS
57-63-6
Formula
C20H24O2
Molecular Weight
296.41000000000003
EINECS
200-342-2
RTECS
RC8925000
RTECS Class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Hormone
Merck
12,3780
Beilstein/Gmelin
2419975
Beilstein Reference
4-06-00-06877

Physical and Chemical Properties

Appearance
Fine white to creamy white powder. A synthetic steroid.
Solubility in water
Insoluble
Melting Point
182-184
pKa/pKb
10.34 (pKa)
Usage
Used in combination with progestogen as an oral contraceptive (merck).

First Aid Measures

Ingestion
DO NOT INDUCE VOMITING. If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. Be prepared to transport the victim to a hospital if advised by a physician. If the victim is convulsing or unconscious, do not give anything by mouth, ensure that the victim's airway is open and lay the victim on his/her side with the head lower than the body. DO NOT INDUCE VOMITING. IMMEDIATELY transport the victim to a hospital.
Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. If symptoms such as redness or irritation develop, IMMEDIATELY call a physician and be prepared to transport the victim to a hospital for treatment.
Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Handling and Storage

Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.

Exposure Controls/Personal Protection

Personal Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Wear a NIOSH-approved half face respirator equipped with a combination filter cartridge, i.e. organic vapor/acid gas/HEPA (specific for organic vapors, HCl, acid gas, SO2 and a high efficiency particulate filter).
Exposure Effects
The toxicological properties of this material have not been investigated.

Fire Fighting Measures

Fire Fighting
Fires involving this compound can be controlled with a dry chemical, carbon dioxide or Halon extinquisher.
Fire Potential
The This material is probably combustible.

Accidental Release Measures

Small spills/leaks
Should a spill occur while you are handling this chemical, FIRST REMOVE ALL SOURCES OF IGNITION, then you should dampen the solid spill material with 60-70% ethanol and transfer the dampened material to a suitable container. Use absorbent paper dampened with 60-70% ethanol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with 60-70% ethanol followed by washing with a soap and water solution. Do not reenter the contaminated area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.

Stability and Reactivity

Incompatibilities
May react vigorously with strong oxidizing agents May react exothermically with reducing agents to generate gaseous hydrogen.
Stability
No data.

Hazards Identification

Hazards
The
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