Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity
Home > 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid > 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid(128-13-2)

3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid(128-13-2)

Supplier Product Identification Physical and Chemical Properties First Aid Measures Handling and Storage Hazards Identification Exposure Controls/Personal Protection Fire Fighting Measures Accidental Release Measures Stability and Reactivity

Product Identification

Product Name
3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid
Synonyms
17b-(1-Methyl-3-carboxypropyl)etiocholane-3a,7b-diol
3a,7b-Dihydroxy-5b-cholanic acid
7b-Hydroxylithocholic acid
Actigall
Ursodesoxycholic acid
Ursofalk
CAS
128-13-2
Formula
C24H40O4
Molecular Weight
392.57
EINECS
204-879-3
RTECS
FZ2000000
RTECS Class
Drug; Mutagen; Reproductive Effector
Merck
12,10026
Beilstein/Gmelin
3219888
Beilstein Reference
4-10-00-01604

Physical and Chemical Properties

Appearance
White powder.
Solubility in water
Insoluble
Melting Point
205
Boiling Point
547
Vapor Pressure
3E-14 (25 C)
pKa/pKb
4.76 (pKa)
Partition Coefficient
4.66
Heat Of Vaporization
95.0 kJ/mol
Usage
Anticholelithic. Used in the treatment of gallstone disease. It is taken by mouth to dissolve the gallstones.

First Aid Measures

Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Handling and Storage

Storage
Store in a tightly closed container. Store in a cool, dry area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.

Hazards Identification

Ingestion
May cause irritation of the digestive tract.
Inhalation
May cause respiratory tract irritation.
Skin
May cause skin irritation.
Eyes
May cause eye irritation.

Exposure Controls/Personal Protection

Personal Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.

Fire Fighting Measures

Flash Point
299
Fire Fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use dry chemical, carbon dioxide, or appropriate foam.

Accidental Release Measures

Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.

Stability and Reactivity

Incompatibilities
Oxidizing agents.
Stability
Stable under normal temperatures and pressures.
Decomposition
Carbon monoxide, carbon dioxide, acrid smoke and fumes.
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