| CAS: | 13721-39-6 |
| MF: | Na3VO4 |
| MW: | 183.91 |
| EINECS: | 237-287-9 |
| Product Categories: | Inhibitors;Inorganics;Peroxidase InhibitorsCell Signaling and Neuroscience;Phosphatase InhibitorsTyrosine Phosphatase Biology;Tyrosine Phosphatase (TP)Chemical Synthesis;Enzyme Inhibitors by Enzyme;Catalysis and Inorganic Chemistry;Chemical Synthesis;Vanadium;Kinase/Phosphatase Biology;P to;Tyrosine Phosphatase Inhibitors |
| Mol File: | 13721-39-6.mol |
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| Sodium orthovanadate Chemical Properties |
| Melting point | 850-866 °C(lit.) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: soluble |
| form | Solid |
| color | off-white |
| Water Solubility | soluble |
| Exposure limits | NIOSH: Ceiling 0.05 mg/m3 |
| Stability: | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 13721-39-6(CAS DataBase Reference) |
| EPA Substance Registry System | Sodium vanadium oxide (Na3VO4) (13721-39-6) |
| Sodium orthovanadate Usage And Synthesis |
| Chemical Properties | white to off-white powder |
| Uses | Sodium orthovanadate is an alkaline phosphatase and (Na,K)-ATPase inhibitor with IC50 of 10 μM. |
| Uses | Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues. |
| Uses | Sodium orthovanadate (Na3VO4) can be used as a metal precursor in the synthesis of:
Vanadium-MCM-48 (V-MCM-48) by anion-exchange method. V-MCM-48 is used as a catalyst in oxidation of styrene to benzaldehyde.
Nanorods of vanadium oxide particles by glycothermal method.
Yttrium vanadate (YVO4) doped with colloidal europium. |
| Definition | ChEBI: Trisodium vanadate is an inorganic sodium salt of formula Na3VO4 containing the tetrahedral VO4(3-) It has a role as an EC 3.1.3.48 (protein-tyrosine-phosphatase) inhibitor, a radiation protective agent, an apoptosis inducer and an antineoplastic agent. It contains a vanadate(3-). |
| Hazard | Poison by ingestion. |
| Biological Activity | Inhibitor of protein tyrosine phosphatases, alkaline phosphatases and ATPases. |
| Biochem/physiol Actions | Sodium orthovandate suppresses the activation of p53-mediated apoptosis triggered in response to radiation. It reduces the detrimental effects of hematopoietic syndrome, hematopoiesis and delayed genotoxic effects of induced by total body irradiation of mice.24 In combination with menadione, orthovandate prevents the migration of detached human glioma cells in response to anti-cancer drugs.25 |
| Safety Profile | Poison by ingestion, intraperitoneal, intravenous, and subcutaneous routes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of VOx and NazO. See also VANADIUM COMPOUNDS. |
| storage | Store at RT |
Product picture
Packing &shipping&Payment
Packing:25kg/drum
Shipping:by sea or by air
Payment:T/T,western union,moneygram
Packaging Details drum
Port:Tianjin
Lead Time :
| Quantity(Kilograms) | 1 - 10000 | >10000 |
| Est. Time(days) | 5 | To be negotiated |
Company information
Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in 4'-Methylacetophenone,Levamisole hydrochloride ,N-Methylformamide and other chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all employees, we have established many cooperative companies in shandong, henan, guangdong and other places. Our corporate purpose is based on the market, enhance the strength, take the road of scientific and environmental sustainable development, relying on the country. Technology r & d center, increase the investment in r & d, based on the domestic market, expand the international market, manufacturing quality products, sincere service to the society, into a modern, ecological, scientific and technological enterprise world.
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