| Product Name | (S)-3-Hydroxy-gamma-buty-rolactonE |
| CAS NO. | 7331-52-4 |
| Appearance | White Powder |
| Purity | 99% |
| Density | 1.241 g/mL at 25 °C(lit.) |
| Boiling Point | 98-100 °C0.3 mm Hg(lit.) |
| Flash Point | >230 °F |
| Refractive Index | n20/D 1.464(lit.) |
| Acidity Coefficient (pKa) | 12.87±0.20 |
| Optical Activity | [α]21/D 81°, c = 2 in ethanol |
| WaterSolubility | Miscible with water, alcohol and other organic solvent. Immiscible with light petroleum. |
| Application | Pharmaceutical intermediates; General reagent |
| Usage | 1. Squalane is widely used as a base material for cosmetics and as a fatting agent for finishing cosmetics, precision machinery lubricants, medical ointments, and high-grade soaps. 2 Squalane is the most commonly used standard non-polar fixative, and its polarity is set to zero. The force of this type of stationary liquid with the component molecules is the dispersion force, which is mainly used to separate general hydrocarbons and non-polar compounds. |
| Storage | Sealed containers at cool and dry place.Protect from sunlight, moisture and pest infestation. |
| Chemical Structure |  |
(S)-3-Hydroxy-gamma-butyrolactone is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S-oxiracetam (S-ORC). It can be deoxidized to (S)-(+)-3-Hydroxytetrahydrofuran which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer.
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