1.Product Description
Molecular Formula C21H22F2N6O2
Molar Mass 428.4352
Density 1.55±0.1 g/cm3(Predicted)
Solubility DMSO: ≥ 4.6 mg/mL
Appearance morphological solid
Color Yellow
pKa 8.41±0.40(Predicted)
Storage Condition Room Temprature
2.Detailed Photos
3.Application
LOXO-101 also known as la rotinib. Legendary anti-cancer drug larotrectinib(LOXO-101) finally received FDA approval in 2018 for the treatment of adults and children with locally advanced or metastatic solid tumors with NTRK gene fusion. The targeted tropomyosin kinase (tropomyosin related kinase, TRK) anti-tumor drug LOXO-101 jointly developed by Loxo Oncology Company and Bayer Company of Germany was approved by FDA on November 26, 2018. The dosage form is capsule and oral liquid. It is used to treat locally advanced or metastatic solid tumors in adults and children with NTRK gene fusion without considering the location of the tumor. The LOXO-101(Larotrectinib) of LOXO Company at the 2017 ASCO Conference has shone a lot of brilliance. The clinical effect of the LOXO-101 has really attracted the attention of many people, because the company with 35 employees has developed Larotrectinib anti-tumor drugs with amazing effect. LOXO-101 target TRK gene is effective for adults or children with locally advanced or metastatic tumors, including 17 cancers such as colon, lung, pancreas, thyroid, saliva and gastrointestinal cancer, with a total remission rate of 75%. It can be said that LOXO-101 is "targeted drug version PD-1".
4.Our advantage
1) Most products on stock, ship out within 1-3 days !
2) Products are tested by QC department strictly before shipping !
3) Make sure the part's safety with our strong shipping line !
4) Customs pass and satisfied rate ≥99% !
5) Responsible for all after-sale quality issues
We guarantee that your package will pass 100% through the Mexico US, UK, Australia, Netherlands, Canada, France, Germany, Spain, Belgium, Sweden, Poland, Russian, Ukraine, Kazakhstan, Czech Republic, Slovakia, Portugal.
We have freight forwarders in these countries, and our customs clearance company will clear your parcels without any customs issues, sometimes even 1000 kg. Door to door service. Make sure you receive 100% of the goods. Let you have a good experience of our strong freight capacity.
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