Chinese name: L-thyroxine
English name :L-Thyroxine
CAS:51-48-9
EINECS number :200-101-1
Molecular formula :C15H11I4NO4
MDL number :MFCD00002596
Molecular weight :776.87
Appearance: white crystal. Mp235-236℃(decomposition), specific rotation [α]20D-4.4°(3%, 0.13 mol/L sodium hydroxide, 70% ethanol), the maximum absorption at 325nm wavelength in 0.4mol/L NaOH solution, and the maximum absorption at 295nm wavelength in 0.4mol/L HCl solution. This product is soluble in alkali solution, insoluble in water, ethanol and ether.
Melting point :235 °C
Specific rotation :-5 º (1N NaOH:EtOH 1:2)
Density :2.4440 (estimate)
Flash point :9℃
Storage conditions :2-8°C
Solubility: 50mg/ml dissolved in 4M ammonium hydroxide methanol solution
Boiling point :576.3±50.0 °C(Predicted)
Acidity factor (pKa):2.2(at 25℃)
Form: Powder
Color: White to light brown
Water solubility :insoluble
Sensitivity: light sensitive
Merck:9491
BRN:2228515
InChIKey:XUIIKFGFIJCVMT-LBPRGKRZSA-N
Use 1
Biochemical research; Thyroxine drugs.
Preparation method
3, 5-diiodo-L-tyrosine was used as the main raw material.
China
