4 - hydroxy isoleucine has improve insulin secretion, insulin resistance and help regulate blood lipid and other aspects.
As Broca and validation for the first time in 1999 4 - hydroxy isoleucine can accelerate the exudation of insulin.The experimental results showed that 4 - hydroxy isoleucine can act directly on the islet beta cells promote insulin secretion, and blood glucose concentration, the higher the stronger role.In 2000 they further research has proved that under the same concentration, only (2 s, 3 r, 4 s) - 4 - HIL can accelerate the exudation of insulin.
4 - hydroxy isoleucine has the function of improving insulin resistance.Central and peripheral tissue insulin resistance including two kinds, the current research week 4 - HIL foreign organization the influence and mechanism of insulin resistance.Broca etc. 4 - hydroxy isoleucine [6] research shows that not only can promote to use the uptake of glucose and surrounding tissue can also decrease hepatic glucose output in order to improve the peripheral tissue insulin resistance.In addition, Ruby and Jaiswal each team studies have shown that 4 - hydroxy isoleucine has a role to raise the capacity of muscle insulin resistance [7].
4 - hydroxy isoleucine also has the role of blood lipid regulation.Sharma, [8] was first reported in 1990, such as fenugreek seeds can reduce blood fat levels.Further animal experiments proved that 4 - hydroxy isoleucine with lower blood lipid.
Diabetes is the 21st century is the most important medical problems, including type 2 diabetes (T2DM) is the fastest growing.At present there are about 150 million people around the world are suffering from T2DM, and for the next 20 years to double that figure is likely to be.It is well known that T2DM is pancreatic beta cells lose insulin secretion function and liver and peripheral insulin resistance ability to reduce [9].Compared to now has been used in the treatment of T2DM drugs, 4 - insulin synthesis of HIL control is strictly dependent on glucose concentration.Therefore, 4 - HIL does not cause side effects such as low blood sugar.In addition to have promote the synthesis of insulin effect, 4 - HIL can also improve the insulin resistance ability of skeletal muscles and organs.The rodent study also found that the 4 - HIL can also be long term is used to control the weight gain and sugar disease [10].In a hamster on dyslipidemia, 4 - HIL can effectively reduce the amount of triglyceride and cholesterol in the blood [11].Therefore, 4 - HIL has very broad application prospects.
Three, product packaging:
Full paper barrel 25 kg bags or aluminum foil bag packing.
China
