Product Name | Perindopril erbumine |
CAS No. | 107133-36-8 |
Appearance | White solid |
Assay | ≥99% |
Capacity | 200mt/year |
MOQ | 100G |
Application | This product is a potent and long-acting angiotensin-converting enzyme inhibitor, which can reduce peripheral vascular resistance without changing cardiac output and heart rate. |
Standard | Enterprise export |
Brand | Lingding |
More Information | Synonyms: 1-[2-(1-Ethoxycarbonylbutylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid 2-methyl-2-propanamine (1:1) Molecular Formula: C19H32N2O5.C4H11N Molecular Weight: 441.61 CAS Registry Number: 107133-36-8 |
Perindopril is a primal blood pressure medicine developed by The French pharmaceutical company Schveal under the trade name Astar. This drug is a long-acting antihypertensive drug. After oral administration, the peak time of the drug is 2-4 hours, and the half-life is 30-120 hours. In China, the allowable dose is 4-8mg once a day. This medicine in addition to the ordinary dosage form, there is a compound preparation "peindopril indapamide tablet", the name of the commodity "Baipule", many domestic hypertension patients have eaten this medicine. Perindopril is an inhibitor of the enzyme (angiotensin converting enzyme) that converts angiotensin I to angiotensin II. This invertase, or kinase, is a peptide-endase that converts angiotensin I into angiotensin Il, which constricts blood vessels. It also degrades bradykinin, which dilates blood vessels, into heptapeptide, which is inactive. Inhibition of angiotensin converting enzyme leads to a decrease in plasma angiotensin ⅱ, which leads to an increase in plasma renin activity (through a negative feedback effect of inhibiting renin release) and a decrease in aldosterone secretion. Because angiotensin invertase inactivates bradykinin, angiotensin invertase allocation inhibition also increases the activity of the circulating and local kallikin-releasing enzyme (and thus prostaglandin system activation) system. This mechanism may be related to the lowering of blood pressure by angiotensin converting enzyme inhibitors or to certain side effects, such as cough. Perindopril works through its active metabolite, perindopril. Other metabolites did not inhibit angiotensin converting enzyme activity in vitro
Packaging & Shipping
Quantity(Metric Tons) | 1 - 1 | 2 - 20 | >20 |
Est. Time(days) | 10 | 25 | To be negotiated |
Company Information
Hebei Lingding Biotechnology Co., Ltd. is a professional business company ,that include pharmaceutical raw materials, pharmaceutical intermediates,and other more than 1000 products of the enterprise, The registered capital is 3 million yuan, it is a collection of scientific research, production and sales in one of the enterprises.
Since its establishment, the company has always adhered to the core concept of "focus on products, attentive service", adhere to the business purpose of "innovation, professional, win-win", to provide customers with a full range of meticulous and thoughtful services. We will adhere to the customer's serious and responsible attitude, comply with the standardized operation procedures, with efficient execution to complete customer needs.
The company's products are sold all over the world, mainly exported to the United States, Europe, Southeast Asia, Australia, the Middle East and South Africa and other countries.The company has a strong scientific research and technical team, can provide customers with high quality products and a full range of services. We will provide first-class products and better service to face the needs of customers, to meet the challenges of the market. Welcome domestic and foreign customers to negotiate.
Our Services
1.Any inquiry or message will be replied within 12 hours.
2.Professional manufacturer. Welcome to visit our website.
3.API, Intermediate are available, we can offer Custom Synthesis, and registration as well.
4.Fast delivery.
5.After-sale services
FAQ
Q1. Are you a manufacturer?
Answer: Yes, we have our own factory.
Q2. Do you have GMP or DMF?
Answer: Yes, we have GMP certificate for some products, and we can provide DMF as well.
Q3. What information should I let you know if I want to get a quotation?
Answer: -Quality you require, eg. Assay, Purity, or single impurity
-Quantity you need
-Standard you want, such as USP, EP, JP etc.
Q4. How to make the payment?
Answer: T/T in advance are highly recommended. We can accept Western Union,
Money Gram and Paypal as well.
Q5. When will you deliver the goods?
Answer: For sample(less than 1kg), in about 3 working days after payment; for larger orders (more than 1kg), in about 7 working days after payment.
Q6. How will you deliver the goods?
Answer: We have strong cooperation with DHL, TNT, UPS, FEDEX, EMS, China Air Post. For container products, we can do sea shipping. You also can choose your own shipping forwarder.
Q7. When will we receive the goods?
Answer: For samples, we will send by TNT/DHL/FEDEX/UPS express, usually it takes about 3-5 to reach you; for larger orders, it will take about 7 -10days at most.
Q8. What if we find your products unsatisfied?
Answer: We will send you a COA (Certificate of Analysis) to you first for you to confirm the quality, but if you find our products not confirm with the COA after you receive it, please show us your test result, we will refund you once we confirm that.
Q9.Do you have stock?
Answer:As we know,most customers prefer stock,so we will try to keep stock for some products.