1445085-77-7
RuPhos PdG3
Synonym: (2-Dicyclohexylphosphino-2′,6′-diisopropoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II) methanesulfonate,
RuPhos-G3-Palladacycle,
RuPhos-Pd-G3
CAS Number: 1445085-77-7
Formula: C43H56NO5PPdS
Formula Weight: 836.37 g/mol
Appearance (Color) White powder
assay 98%
mp 188-196 °C (decomposition)
Caution : air sensitive
shelf life :12 month
ISO9001 Manufacturer
Standard laboratory
ligands catalysts synthesis compounds
Supplier: LPBchem-Benjamin
Related Categories
Buchwald 3rd Generation Palladacycles, Buchwald Ligands and Complexes, Catalysis and Inorganic Chemistry, Chemical Synthesis, Cross-Coupling,
Homogeneous Pd Catalysts, Palladium Catalysts
General description
RuPhos Pd G3 is a third generation (G3) Buchwald precatalyst that can be used in cross-coupling reactions for the formation of C-C, C–N, C–O, C–F, C–CF3, and C–S bonds. It is air-, moisture-, and thermally-stable and is highly soluble in a wide range of common organic solvents. Some of its unique features include lower catalyst loadings, shorter reaction time, efficient formation of the active catalytic species and accurate control of ligand: palladium ratio.
Application
RuPhos Pd G3 can be used as a pre-catalyst in the following protocols:
1 Palladium-catalyzed Suzuki coupling of 5-p-toluenesulfonyltetrazoles with arylboronic acids to synthesize 1,5-disubstituted tetrazoles.
2 Suzuki-Miyaura catalyst-transfer polycondensation (SCTP) of 3-alkylthiophenes in the presence of N-methylimidodiacetic (MIDA)-boronate monomers.
3 Suzuki-Miyaura-cross-coupling of aminothiophenes.
Hazard statement(s)
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H412 Harmful to aquatic life with long lasting effects.
China
