1. Product information
Names
| Name | N-[3-(Acetylthio)-(2S)-methylpropionyl]-L-proline hydrate |
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| Synonym | More Synonyms |
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Captopril EP Impurity J Biological Activity
| Description | Captopril EP Impurity J is an impurity of Captopril. Captopril (SQ-14534), antihypertensive agent, is a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor (IC50=0.025 μM)[1][2][3]. |
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| Related Catalog | Research Areas >> Others Signaling Pathways >> Others >> Others |
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| References | [1]. Li, Hp, et al. Synthesis and characterization of captopril derivatives. Res Chem Intermed 39, 621–629 (2013). [2]. Afrin S, et al. Eritadenine from Edible Mushrooms Inhibits Activity of Angiotensin Converting Enzyme in Vitro. J Agric Food Chem. 2016;64(11):2263-2268. [3]. Esmaeili S, et al. Captopril/enalapril inhibit promiscuous esterase activity of carbonic anhydrase at micromolar concentrations: An in vitro study. Chem Biol Interact. 2017;265:24-35. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 464.8±40.0 °C at 760 mmHg |
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| Melting Point | 76-82 °C(lit.) |
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| Molecular Formula | C11H17NO4S |
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| Molecular Weight | 259.322 |
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| Flash Point | 234.9±27.3 °C |
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| Exact Mass | 259.087830 |
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| PSA | 99.98000 |
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| LogP | 0.40 |
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| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
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| Index of Refraction | 1.549 |
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2. Packaging
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping
4. Contact information
For more details, pls contact us freely.
Email address : sun@fdachem.com
Mob: 86 13526505137
WhatsApp/Skype/Wechat/: 86 13526505137
China
