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外観
白色/無色～うすい黄赤色～黄色粉末～塊～透明液体
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化学的特性
clear brown liquid
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使用
4-Chloro-2-methylaniline may be used in the synthesis of the following:
- 2,8-dichloro-4,10-dimethyl-6H,12H-5,11-methanodibenzo[b,f]-diazocine via reaction with paraformaldehyde in toluene
- N-allylated derivative via palladium-catalyzed selective monoallylation with allyl alcohol
- N-(4-chloro-2-methylphenyl)benzamide via reaction with benzoyl chloride
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一般的な説明
Gray to white solid with a weak fishy odor. Sinks in water. Freezing point is 77°F.
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空気と水の反応
May be sensitive to prolonged exposure to air and light. Insoluble in water.
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反応プロフィール
4-Chloro-2-methylaniline is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizing agents. . A halogenated amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
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危険性
Toxic by ingestion and inhalation. Probable
carcinogen.
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健康ハザード
Inhalation, ingestion, or skin contact causes bluish tint in fingernails, lips, and ears. Headache, drowsiness, and nausea also occur. Contact with eyes causes irritation.
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火災危険
Special Hazards of Combustion Products: Toxic oxides of nitrogen and hydrochloric acid fumes may form.
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安全性プロファイル
Confirmed carcinogen.
Poison by ingestion and subcutaneous
routes. Human mutation data reported. In
the presence of copperpI) chloride catalyst
decomposition occurs above 239'C. When
heated to decomposition it emits toxic
fumes of Cland NOx. See also other chloro
toluidme entries.
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職業ばく露
Most of the isomers are used in dyestuff manufacture. The 3-chloro-para isomer is used to kill
birds. It is marketed as pelleted bait for control of bird
populations.
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発がん性
p-Chloro-o-toluidine and its hydrochloride salt are reasonably anticipated to be human carcinogens based on limited evidence of carcinogenicity from studies in humans and evidence of carcinogenicity from studies in experimental animals.
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輸送方法
UN2239 Chlorotoluidines, solid, Hazard Class:
6.1; Labels: 6.1-Poisonous materials. UN3429
Chlorotoluidines, liquid, Hazard Class: 6.1; Labels: 6.1-
Poisonous materials
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不和合性
Incompatible with oxidizers, strong
acids; chloroformates, and acid anhydrides, isocyanates,
aldehydes forming fire and explosive hazards.
