(+)-ウスニン酸

外観

黄色～暗黄色, 結晶～結晶性粉末

溶解性

水に不溶。エタノール, ベンジンに難溶。クロロホルム, ベンゼンに易溶。水に溶けない。エタノール、ベンジンに溶けにくく、クロロホルム、ベンゼンに溶けやすい。クロロホルムに溶け、エタノールに極めて溶けにくく、水にほとんど溶けない。

特長

生物学的性質 : 試験管内においてグラム陽性菌、結核菌などに対して成長抑制作用がある。

使用

Usnic acid is used as fragrance; preservative in deodorants; in anti ac ne formulations; antibiotic for topical application.

一般的な説明

(+)-Usniacin is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.

接触アレルゲン

Usnic acid is a component of lichens, also used as a topical antibiotic. Allergic contact dermatitis from lichens occurs mainly occupationally in forestry and horticultural workers, and in lichen pickers.

純化方法

This very weak acid is the natural form which is recrystallised from Me2CO, MeOH or *C6H6. At 25o it is soluble in H2O (<0.01%), Me2CO (0.77%), EtOAc (0.88%), MeOCH2CH2OH (0.22%) and furfural (7.32%). [Curd & Robertson J Chem Soc 894 1937, Barton & Brunn J Chem Soc 603 1953, resolution: Dean et al. J Chem Soc 1250 1953, synthesis: Barton et al. J Chem Soc 538 1956, Beilstein 18/5 V 586.]