-
外観
白色～うすい褐色, 結晶性粉末～粉末
-
定義
本品は、イナゴマメ Ceratonia Siliqua の子葉部から得られる多糖体である。
-
溶解性
熱水に溶け、エタノール及びアセトンに溶けない。
-
用途
主に、食品工業では増粘剤や品質改良剤として、製紙工業ではサイジング剤として用いられる。
-
化粧品の成分用途
結合剤、親水性増粘剤、乳化安定剤、香料、粘着剤
-
化学的特性
branched, nonionic polymer.
-
物理的性質
It is a white to yellowish-white powder. It is dispersible in either hot or cold water, forming a
solution having a pH between 5.4 and 7.0, which may be converted to gel by the addition of small amounts of sodium borate.
-
使用
Locust Bean Gum is a gum that is a galactomannan obtained from
the plant seed from the locust bean tree known as ceratonia siliqua.
it has a mannose:galactose ratio of approximately 4:1. its properties
include swelling partially in cold water but requiring heating to
approximately 82°c for complete solubility. it provides high viscos-
ity, forms gels with xanthan gum upon heating and cooling of the
solution, and functions as a water binder. it can make agar or car-
rageenan gels more elastic. its uses include processed cheese, ice
cream, bakery products, soups, and pies. typical usage level is 0.1–
1.0%. it is also called carob gum or saint john’s bread, and is scien-
tifically called carubin.
-
調製方法
Ceratonia is a naturally occurring material obtained from the
ground endosperms separated from the seeds of the locust bean tree,
Ceratonia siliqua (Leguminosae). The tree is indigenous to southern
Europe and the Mediterranean region.
-
一般的な説明
Off-white to yellow-green powder. Odorless and tasteless, but acquires a leguminous taste when boiled in water.
-
空気と水の反応
Insoluble in water.
-
健康ハザード
ACUTE/CHRONIC HAZARDS: When heated to decomposition LOCUST BEAN GUM emits acrid smoke and fumes.
-
火災危険
Flash point data for LOCUST BEAN GUM are not available. However, LOCUST BEAN GUM is probably combustible.
-
応用例（製薬）
Ceratonia is a naturally occurring material generally used as a
substitute for tragacanth or other similar gums. A ceratonia
mucilage that is slightly more viscous than tragacanth mucilage
may be prepared by boiling 1.0–1.5% of powdered ceratonia with
water. As a viscosity-increasing agent, ceratonia is said to be five
times as effective as starch and twice as effective as tragacanth.
Ceratonia has also been used as a tablet binder and is used in oral
controlled-release drug delivery systems approved in Europe and
the USA.
Ceratonia is widely used as a binder, thickening agent, and
stabilizing agent in the cosmetics and food industry. In foods,
0.15–0.75% is used. Therapeutically, ceratonia mucilage is used
orally in adults and children to regulate intestinal function.
-
安全性プロファイル
Mildly toxic by
ingestion. When heated to decomposition it
emits acrid smoke and irritating fumes.
-
安全性
Ceratonia is generally regarded as an essentially noncarcinogenic,
nontoxic and nonirritant material. Therapeutically, it has been used
in oral formulations for the control of vomiting and diarrhea in
adults and children; 20–40 g daily in adults has been used dispersed
in liquid. As an excipient, ceratonia is used in oral controlledrelease
formulations approved in Europe and the USA.
Ceratonia is also widely used in food products. The WHO has
not specified an acceptable total daily intake for ceratonia as the
total daily intake arising from its use at the levels necessary to
achieve the desired effect, and from its acceptable background in
food, was not considered to represent a hazard to health.
Ceratonia hypersensitivity has been reported, in a single case
report, in an infant. However, ceratonia is said to be nonallergenic
in children with known allergy to peanuts.
LD50 (hamster, oral): 10.0 g/kg
LD50 (mouse, oral): 13.0 g/kg
LD50 (rabbit, oral): 9.1 g/kg
LD50 (rat, oral): 13.0 g/kg
-
貯蔵
The bulk material should be stored in a well-closed container in a
cool, dry place. Ceratonia loses not more than 15% of its weight on
drying.
-
不和合性
The viscosity of xanthan gum solutions is increased in the presence
of ceratonia. This interaction is used synergistically in controlledrelease
drug delivery systems.
-
規制状況(Regulatory Status)
GRAS listed. Accepted for use in Europe as a food additive. In
Europe and the USA, ceratonia has been used in oral tablet
formulations.
