-
外観
黄色〜黄赤色, 結晶性粉末〜粉末
-
溶解性
水に殆ど不溶。エタノールにやや溶けにくい。熱エタノール, アセトンに可溶。ジエチルエーテルにやや溶けにくく、エタノールに溶けにくく、水にほとんど溶けない。
-
解説
C14H15N3(225.29)．ジメチルイエロー(Dimethyl Yellow)，バターイエロー(Butter Yellow)ともいう．アニリンとN,N-ジメチルアニリンの塩酸溶液に亜硝酸ナトリウム水溶液を加え，低温でジアゾカップリングすることにより得られる．黄色の結晶．融点117 ℃．染料および食品の着色料として使用されていたが，発がん性物質であることがわかったので，現在は使われていない．[CAS 60-11-7]
森北出版「化学辞典（第2版）
-
用途
調製液原料。変異原性・がん原性物質試験研究用。
-
用途
染料、染料中間体
-
説明
4-N,N-Dimethylaminobenzene diazonium chloride is a
diazo compound found in diazo copy paper. It is
allergenic only when unexposed.
-
化学的特性
yellow to orange crystalline powder
-
使用
For determination of free HCl in gastric juice; spot test identification of peroxidized fats; pH indicator (red 2.9, yellow 4.0).
-
定義
A banned food coloring.
-
製造方法
aniline diazotization, and N,N-dimethylaniline coupling.
-
調製方法
4-Dimethylaminoazobenzene was produced in large quantities
in the early 1900s but is currently not produced in
any significant commercial quantity in the United States.
-
一般的な説明
Yellow crystalline leaflets or an orange powder.
-
空気と水の反応
Dust may form an explosive mixture in air. Insoluble in water.
-
反応プロフィール
Solvent Yellow 2 can detonate, particularly if sensitized by the presence of metal salts or strong acids. May form toxic gases with acids, aldehydes, amides, carbamates, cyanides, inorganic fluorides, halogenated organics, isocyanates, ketones, metals, nitrides, peroxides, phenols, epoxides, acyl halides, and strong oxidizing or reducing agents. May form flammable gases with alkali metals. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides. May react explosively with strong oxidizing agents, metal salts, peroxides, and sulfides.
-
危険性
Carcinogen.
-
健康ハザード
4-Dimethylamino-azobenzene (XIII) is the parent compound of the amino-azo dye carcinogens; it is also known in the earlier literature as Butter Yellow, because it was used to color butter and vegetable oils before its carcinogenic activity was discovered. Many derivatives of XIII have been prepared and tested for carcinogenic activity. In the rat, the amino-azo dye carcinogens, administered in the diet, specifically induce hepatomas. Tumor induction by most of the amino-azo dyes is delayed or inhibited by high dietary levels of riboflavin (vitamin B2) or protein. Replacement of the –N=N– azo linkage by –CH=CH–, as in 4-dimethylaminostilbene (XIV), results in widening the target tissue spectrum; XIV induces tumors in the liver, mammary gland, and ear duct. Mice are much more resistant than rats to the carcinogenic activity of both amino-azo dyes and aminostilbenes.
-
火災危険
Flash point data for Solvent Yellow 2 are not available. Solvent Yellow 2 is probably combustible.
-
安全性プロファイル
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, and tumorigenic data. Poison
by ingestion and intraperitoneal routes.
Experimental teratogenic and reproductive
effects. Human mutation data reported.
When heated to decomposition it emits
toxic fumes of NOx
-
発がん性
4-Dimethylaminoazobenzene is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity fromstudies in experimental animals.
-
環境運命予測
Chemical/Physical. Releases toxic nitrogen oxides when heated to decomposition (Sax and
Lewis, 1987).
At influent concentrations of 1.0, 0.1, 0.01, and 0.001 mg/L, the GAC adsorption capacities
were 249, 140, 83, and 48 mg/g, respectively (Dobbs and Cohen, 1980).
-
純化方法
Crystallise the dye from acetic acid or isooctane, or from 95% EtOH by adding hot water and cooling. Dry it over KOH under vacuum at 50o. [Beilstein 6 IV 448.] CARCINOGEN.
