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外観
無色～うすい黄色、澄明の液体
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溶解性
水に不溶, エタノール, エーテルに混和。エタノール(99.5)及びアセトンに溶け、水にほとんど溶けない。
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用途
医薬?香料原料,食品添加物(香料)
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化学的特性
Propiophenone has a strong, flowery odor. 1-Phenyl-1-propanone is a colorless liquid with a flowery odor, insoluble in water, readily soluble in organic solvents. Typical reactions can be carried out at the methylene group, the carbonyl group, and at the aromatic nucleus.
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天然物の起源
Reported found in coffee, roasted filberts, roasted peanuts and roasted green tea. Also reported found in
Camembert cheese, black tea, roasted macadamia nut, tamarind, dried bonito, cherimoya and sapodilla fruit.
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使用
Propiophenone is an aryl ketone used in the preparation of pharmaceutical and organic compounds. Propiophenone is used in perfumes as well as in the preparation of neurochemical compounds such as ephe
drines.
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定義
ChEBI: Propiophenone is an aromatic ketone in which the two substituents on the carbonyl C atom are phenyl and ethyl. It has a role as a fragrance.
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調製方法
Propiophenone is produced by the Friedel–Crafts acylation
of benzene with propionic acid chloride in the presence of
aluminum chloride. It may also be produced by the reaction
of benzoic acid and propionic acid using a calcium acetate–
aluminum oxide catalyst.
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安全性プロファイル
Poison by
intraperitoneal route. Moderately toxic by
subcutaneous route. Mildly toxic by
ingestion and skin contact. A skin and eye
irritant. A flammable liquid when exposed to
heat or flame; can react with oxidizing
materials. To fight fire, use foam, CO2, dry
chemical. When heated to decomposition it emits acrid smoke and irritating fumes. See
also KETONES.
