アリルスルフィド

外観

無色～ほとんど無色透明液体

解説

ジアリルスルフィド，無色の液体．融点－83 ℃，沸点139 ℃．d₄²⁷"0.88765．n_D²⁷"1.4877．水に不溶，エタノール，クロロホルム，エーテルに可溶．塩化水銀(Ⅱ)，塩化白金(Ⅱ)と錯化合物をつくる．

製造

硫化アリル，硫化ジアリルともいう．ニンニク油中にその二硫化物とともに存在する．また，ネギ，タマネギの臭いはこの化合物による．ヨウ化アリルと硫化カリウムから得られるジアリルスルフィド．

用途

食品用香料として用いられる．

化学的特性

clear colorless liquid

天然物の起源

Reported found in garlic (Allium sativum L.), onion (Allium cepa L.), nira (Allium tuberosum Rottl.), caucas (Allium victoralis L.), mustard (Brassica species) and cooked/boiled beef

使用

Diallyl sulfide is a modulator of drug metabolizing enzyme P450 system and inducer of the phase II detoxifying enzyme GST. Diallyl sulfide is also an inhibitor of CYP2E1 and believed to prevent chemically-induced carcinogenesis in many tissues. It is also used as a food additive. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

製造方法

From allyl iodide plus potassium sulfide in alcoho

一般的な説明

Allyl sulfide is a volatile flavor compound naturally found in Allium species such as garlic and onion. It is has a characteristic garlic odor and is used as a flavoring agent in meat and condiments.

抗がん研究

It is a thioether, found in garlic, inhibits cytochrome P450 IIE1 isoform, and therebysuppresses carcinogenesis (Aggarwal and Shishodia 2004). The consumption ofgarlic provides protection from gastrointestinal cancers and also suppresses theprogression of colorectal adenomas (Hosseini and Ghorbani 2015).