基本属性 生物活性体外研究体内研究 用途与合成方法 乙格列酯 价格(试剂级) 供应商 相关产品
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乙格列酯

乙格列酯

中文名称:乙格列酯
英文名称:1,5-dideoxy-1,5-[[2-[4-(ethoxycarbonyl)phenoxy]ethyl]imino]-D-glucitol
CAS号:80879-63-6
分子式:C17H25NO7
分子量:355.38
EINECS号:279-613-2
Mol文件:80879-63-6.mol
乙格列酯 结构式

乙格列酯 性质

沸点 580.2±50.0 °C(Predicted)
密度 1.328±0.06 g/cm3(Predicted)
储存条件 Store at -20°C
溶解度 溶于二甲基亚砜
酸度系数(pKa) 13.68±0.70(Predicted)

乙格列酯 用途与合成方法

Emiglitate (BAY o 1248)是有效的,竞争选择性的α-glucoside hydrolase抑制剂。

Emiglitate greatly suppresses the glucose-stimulated insulin release in parallel with an inhibitory effect on the activities of acid glucan-1,4-α-glucosidase and acid α-glucosidase. In contrast, the activities of acid phosphatase and N-acetyl-β-D-glucosaminidase tend to increase in the presence of the α-glucoside hydrolase inhibitor. The CO-induced amplification of the glucose-stimulated insulin release as well as of the increased activities of the acid α-glucoside hydrolases are abrogated by emiglitate and displayed the same levels as in the absence of CO. The CO-induced rise in the activities of acid phosphatase and acid N-acetyl-β-D-glucosaminidase is not appreciably affected by emiglitate.

In fasted rats, emiglitate inducec a significant, dose-dependent increase of hepatic glycogen concentrations. The increase in hepatic glycogen is due to lysosomal storage of glycogen only. Emiglitate in the amount of 5 mg/kg b.wt. does not induce significant changes either of glycogen concentrations or at the EM-level.

乙格列酯 价格(试剂级)

更新日期 产品编号 产品名称 CAS号 包装 价格
2024-01-25 HY-16194 乙格列酯 80879-63-6 1mg 5072

乙格列酯供应商 更多

ChemeGen 中国
联系电话: 18818260767
产品介绍:
英文名称:Emiglitate
CAS:80879-63-6
纯度:98%
包装信息:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
备注:品牌:ChemeGen
天津普西唐生物医药科技有限公司
联系电话:010-60605840 15801484223
产品介绍:
英文名称:Emiglitate
CAS:80879-63-6
包装信息:1mg
备注: 试剂级
TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物 T15215
英文名称:Emiglitate;Emiglitate
CAS:80879-63-6
纯度:98%
包装信息:5 mg

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