基本属性 生物活性靶点体外研究 用途与合成方法 供应商

131999-28-5

131999-28-5

中文名称:131999-28-5
英文名称:1H-Isoindole-1,3(2H)-dione, 2-[2-[4-(6-fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-
CAS号:131999-28-5
分子式:C22H20FN3O3
分子量:393.41
EINECS号:
Mol文件:131999-28-5.mol
131999-28-5 结构式

131999-28-5 性质

沸点 565.6±50.0 °C(Predicted)
密度 1.346±0.06 g/cm3(Predicted)
酸度系数(pKa) 7.86±0.10(Predicted)

131999-28-5 用途与合成方法

5-HT6/7 antagonist 1是多功能的 5-HT6/7/2A 和 D2 受体拮抗剂,但不与M1受体和hERG通道相互作用。

5-HT 6 Receptor

5-HT 7 Receptor

5-HT 2A Receptor

D 2 Receptor

Targeting 5-HT6 and/ or 5-HT7 receptors with antagonist drugs could constitute a promising strategy for treating symptoms of BPSD while avoiding some of the side effects of current antipsychotic drugs. Nevertheless, due to the complex pathology of dementia and accompanying behavioral and psychological symptoms, it seems unlikely that focusing on a single therapeutic target would be sufficient to provide adequate clinical benefit, and it is likely that successful development of novel anti-BPSD agents should involve a “designed” multifactorial approach.

131999-28-5供应商 更多

天津普西唐生物医药科技有限公司
联系电话:010-60605840 15801484223
产品介绍:
英文名称:5-HT6/7 antagonist 1
CAS:131999-28-5
包装信息:100mg
备注: 试剂级
TargetMol中国(陶术生物)
联系电话: 4008200310
产品介绍:
中文名称:化合物 5-HT6/7 antagonist 1
英文名称:5-HT6/7 antagonist 1
CAS:131999-28-5
纯度:98%
包装信息:100 mg;5 mg;50 mg