2,3-ジメチルマレイン酸無水物

外観

白色～うすい黄褐色、結晶～結晶性粉末

解説

2,3-ジメチルマレイン酸無水物，ジメチルマレインサンムスイブツ，3,4-dimethyl-2,5-furandione．C6H6O3(126.11)．2,3-ジメチルマレイン酸と塩化アセチルとを加熱すると得られる．板状晶または葉状晶．融点93 ℃，沸点223 ℃．d¹⁹₄0.9092．エタノール，エーテル，クロロホルム，ベンゼンに可溶，冷水に難溶．水蒸気蒸留される．アルカリで処理すると2,3-ジメチルフマル酸を与える．殺菌剤，殺虫剤，除草剤，枯葉剤などの合成原料に用いられる．

用途

有機合成原料。

化学的特性

white to beige crystals or cryst. powder

使用

2,3-Dimethylmaleic anhydride can be usually used in the synthesis of maleimides and as an amino group protecting agent for superoxide dismutase. It is also used in the preparation of dimethylmaleic acid dimethyl ester. Further, it serves as a reactant in the dissociation of ribosomal proteins. In addition to this, The isolated molecule 2, 3-dimethylmaleic anhydride showed potent insecticidal activity in fumigation bioassay against several insect species, viz., adults of houseflies, cockroaches and stored-product insects.

定義

ChEBI: 2,3-Dimethylmaleic anhydride is a butenolide. It is a 5-membered cyclic anhydride with a double bond between carbon atoms C2 and C3. The double bond locks the molecule in a planar conformation and stabilizes the acid anhydride against hydration. It was used as linker to a cell penetrating peptidebased nanoparticle.

安全性プロファイル

Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits acrid smoke and irritating fumes. See also ANHYDRIDES.

純化方法

Distil the anhydride from *benzene/ligroin and sublime in a vacuum. [Beilstein 17/11 V 69.]