-
化学的特性
yellow to yellow-green crystalline powder
-
物理的性質
Crystalline, solid, prisms, or plates. Benzo[e]pyrene is sensitive to ultraviolet light and may
degrade into diones.
-
使用
Used for studies of immune suppressive activity of bezo[e]Pyrene on antibody response to DNP-Ficoll and sheep erythrocytes and "dispersive liquid -liquid micro extraction” technique by extracting organic compounds from water samples.
-
定義
ChEBI: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings. It is listed as a Group 3 carcinogen by the IARC.
-
一般的な説明
Colorless crystals or white crystalline solid.
-
空気と水の反応
Insoluble in water.
-
反応プロフィール
BENZO[E]PYRENE may be sensitive to prolonged exposure to light.
-
健康ハザード
There is very little information available onits toxicity. The oral toxicity is expected to below. Its carcinogenic potential is lower thanthat of benz[a]pyrene. Animal studies gaveinconclusive results. Oral administration mayproduce tumors in the stomach. However, theevidence of carcinogenicity of this compoundin animals is inadequate. Benz[e]pyrene isa mutagen, testing positive to the histidinereversion–Ames test and in vitro unscheduled DNA synthesis (UDS)–human fibroblast.
-
火災危険
Flash point data for BENZO[E]PYRENE are not available. BENZO[E]PYRENE is probably combustible.
-
安全性プロファイル
For occupational chemicalanalysis use NIOSH: Polynuclear Aromatic Hydrocarbons(HPLC), 5506; (GC), 5515.
-
環境運命予測
Photolytic. Schwarz and Wasik (1976) reported a fluorescence quantum yield of ≈ 0.3 for
benzo[e]pyrene in water.
Chemical/Physical. Benzo[e]pyrene will not hydrolyze because it has no hydrolyzable
functional group.
-
純化方法
Purify it by passage through an Al2O3 column (Woelm, basic, activity I) and elute with *C6H6 and recrystallise from 2 volumes of EtOH/*C6H6 (4:1). It forms colourless or light yellow prisms or needles. [Campbell J Chem Soc 3659 1954, Buchta & Kr.ger Justus Liebigs Ann Chem 705 190 1967.] The 1,3,5-trinitrobenzene complex has m 253-254o (orange needles from EtOH), the picrate prepared by mixing 20mg in 1mL of *C6H6 with 20mg of picric acid in 2mL *C6H6, collecting the deep red crystals, and recrystallising from *C6H6 has m 228-229o [NMR: Cobb & Memory J Chem Phys 47 2020 1967]. [Beilstein 5 III 2520, 5 I V 2689.] CARCINOGEN.