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説明
Chlorophacinone is produced by condensation of 1-
phenyl-1-(4-chlorophenyl) acetone with dimethyl phthalate
in the presence of sodium methoxide (31).
This compound was introduced in 1961 and is now
widely used in Europe, the United States, and elsewhere.
It is used in baits against norway rats at a concentration
of 0.005–0.01%. Bait containing 0.025% chlorophacinone
gave a complete kill of house mice after a 7-d feeding
period but, in other tests, survivors were recorded following
10 and 21 days of feeding (5). Chlorophacinone acts as
an uncoupler of oxidative phosphorylation as well as an
anticoagulant (32), which is unusual among this group of
compounds.
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化学的特性
Chlorophacinone is a highly toxic crystalline
solid.
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使用
Chlorophacinone (CPN) is an anticoagulant rodenticide widely used to control rodent infestations.
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一般的な説明
Crystals. Commercially available as oil concentrate and as dust concentrate. Used as an anticoagulant rodenticide. Chronic acting, multiple dose rodenticide.
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空気と水の反応
Insoluble in water.
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反応プロフィール
Fire may produce irritating or poisonous gases.
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健康ハザード
Chlorphacinon is highly toxic orally and by skin absorption. The probable oral lethal dose for humans is less than 5 mg/kg to 50 mg/kg, or between a taste (less than 7 drops) and 1 teaspoonful for a 150 lb. (70 kg) person.
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火災危険
(Non-Specific -- Coumarin Derivative Pesticide, Solid, n.o.s.) Fire may produce irriating or poisonous gases. Runoff from fire control water may give off poisonous gases. Runoff from fire control or dilution water may cause pollution. When heated Chlorphacinon emits toxic fumes of chlorides.
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农业用途
Rodenticide: This material is an anticoagulant rodenticide used around livestock and also on crops such as artichokes. Some brands are labeled for use indoors and outdoors for the control of mice, rats, moles, muskrats, voles and vampire
bats. Not approved for use in EU countries. Registered for use in the U.S. There are 24 global suppliers.
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製品名
AFNOR®; CAID®; DELTA®; DRAT RAT BAIT®; ENDORATS®; LIPHADIONE®; LM 91®; MICROZUL®; MURIOL®; PARTOX®[C]; QUICK®; RAMUCIDE®; RANAC®; RATOMET®; RAVIAC®; ROZOL®[C]; TOPITOX®
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安全性プロファイル
Poison by ingestion and
skin contact. Human systemic effects by
ingestion: vascular changes. A pesticide. When heated to decomposition it emits
toxic fumes of Cl-.
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職業ばく露
Agricultural Chemical. This material
is an anticoagulant rodenticide. A potential danger to those
involved in its manufacture, formulation, and application
are at risk.
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輸送方法
UN3027 Coumarin derivative pesticides, solid,
toxic, Hazard Class: 6.1; Labels: 6.1-Poisonous materials.
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廃棄物の処理
Incineration at high temperature with effluent gas scrubbing.
